Drugs / CISH Inactivated TIL
last change Nov 2025 re-read 2 minutes ago

CISH Inactivated TIL

Cell therapy targets CISH via inhibition

Developed for
large cell carcinoma · lung adenocarcinoma · squamous cell lung carcinoma
Investigated by
Intima Bioscience, Inc.

Trials 1 · a red edge is where a trial was stopped

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05566223 Feb 2023 → Nov 2025 large cell carcinoma, lung adenocarcinoma, squamous cell lung carcinoma Intima Bioscience, Inc. Withdrawn No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CISH Inactivated TIL ClinicalTrials.gov intervention name — accepted as the source's own label NCT05566223
Action Inhibit “the intracellular immune checkpoint CISH has been inhibited” NCT05566223
Modality Cell therapy “genetically-engineered Tumor Infiltrating Lymphocytes (TIL)” NCT05566223
Route Intravenous “CISH inactivated TIL for infusion will be administered intravenously (IV)” NCT05566223
Target CISH “the intracellular immune checkpoint CISH has been inhibited” NCT05566223