Drugs / Anumigilimab
last change Feb 2026 re-read 3 minutes ago

Anumigilimab

also known as CSL324

Monoclonal antibody targets CSF3R via inhibition

Developed for
COVID-19 · hidradenitis suppurativa · palmoplantar pustulosis · sickle cell disease
Investigated by
CSL Behring

Trials 5

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT05653713 Dec 2022 → Jul 2023 — CSL Behring Completed No outcome recorded
Phase 1 NCT04570267 Oct 2020 → Nov 2021 — CSL Behring Completed No outcome recorded
Phase 1 NCT03972280 Jul 2019 → Oct 2022 hidradenitis suppurativa, palmoplantar pustulosis CSL Behring Completed No outcome recorded
Phase 22 trials
Phase 2 NCT07224360 Feb 2026 → Jun 2028 expected sickle cell disease CSL Behring Recruiting No outcome recorded
Phase 2 NCT04519424 Sep 2020 → Apr 2021 COVID-19 CSL Behring Withdrawn No outcome recorded Stop: Business

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Anumigilimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT07224360 ↗
Known as CSL324 “Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)” NCT07224360 ↗
4

“CSL324” NCT03972280 ↗

NCT04570267 ↗

NCT04519424 ↗

NCT05653713 ↗

Action Inhibit “Granulocyte colony stimulating factor receptor antagonist” CHEMBL4650461 ↗
Modality Monoclonal antibody “recombinant anti-granulocyte colony-stimulating factor (G-CSF) receptor monoclonal antibody” NCT03972280 ↗
Route Intravenous “suitable for intravenous infusion” NCT03972280 ↗
Target CSF3R “Granulocyte colony stimulating factor receptor antagonist” CHEMBL4650461 ↗