Drugs / Bavdegalutamide
last change Apr 2025 re-read 2 minutes ago

Bavdegalutamide

also known as ARV-110 · ARV-110 (PROTAC)

Small molecule targets AR

Developed for
metastatic prostate carcinoma
Investigated by
Arvinas Inc. · Arvinas Inc.

Trials 2 · a red edge is where a trial was stopped

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05177042 May 2022 → Jul 2024 metastatic prostate carcinoma Arvinas Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03888612 Mar 2019 → Apr 2024 metastatic prostate carcinoma Arvinas Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as bavdegalutamide Bavdegalutamide (ARV-110) is a PROteolysis TArgeting Chimera (PROTAC) protein degrader that recruits the cereblon-containing E3 ubiquitin ligase to direct the...” PMID 39670468 Apr 2025
1

NCT05177042

Known as ARV-110 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03888612
Known as ARV-110 (PROTAC) ChEMBL registry synonym — accepted as the source's own label CHEMBL4862963
Modality Small molecule CHEMBL4862963
Route Oral “Part A: Oral tablet(s), once or twice daily in 28 day cycles” NCT03888612
Target AR “Bavdegalutamide (ARV-110) is a PROteolysis TArgeting Chimera (PROTAC) protein degrader that recruits the cereblon-containing E3 ubiquitin ligase to direct the...” PMID 39670468 Apr 2025