Drugs / RAMATERCEPT
last change Jun 2011 re-read 3 minutes ago

RAMATERCEPT

also known as ACE-031

Protein / enzyme biologic targets MSTN via inhibition

Developed for
Duchenne muscular dystrophy
Investigated by
Acceleron Pharma, Inc.

Trials 4

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00952887 Aug 2009 → Feb 2011 muscular atrophy Acceleron Pharma, Inc. Completed No outcome recorded
Phase 1 NCT00755638 Sep 2008 → Jul 2009 muscular atrophy Acceleron Pharma, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01239758 Oct 2010 → May 2011 Duchenne muscular dystrophy Acceleron Pharma, Inc. Terminated No outcome recorded
Phase 2 NCT01099761 Apr 2010 → Jun 2011 Duchenne muscular dystrophy Acceleron Pharma, Inc. Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as RAMATERCEPT ChEMBL registry synonym — accepted as the source's own label CHEMBL2108674 ↗
Known as ACE-031 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00755638 ↗
3

NCT01099761 ↗

NCT01239758 ↗

NCT00952887 ↗

Action Inhibit “Growth/differentiation factor 8 inhibitor” CHEMBL2108674 ↗
Modality Protein / enzyme biologic “ACE-031, a soluble form of the human activin receptor type IIB” NCT01099761 ↗
Route Subcutaneous “single subcutaneous dose of ACE-031” NCT00755638 ↗
Target MSTN “Growth/differentiation factor 8 inhibitor” CHEMBL2108674 ↗