Drugs / BGB-3245
last change Mar 2025 re-read 9 days ago

BGB-3245

Developed for
colorectal cancer · neoplasm · pancreatic ductal adenocarcinoma
Investigated by
MapKure, LLC · SpringWorks Therapeutics, Inc.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06194877 Apr 2024 → Mar 2025 colorectal cancer, pancreatic ductal adenocarcinoma MapKure, LLC Terminated No outcome recorded Stop: Business
Phase 1/21 trial
Phase 1/2 NCT05580770 Feb 2023 → Jan 2025 neoplasm SpringWorks Therapeutics, Inc. Terminated No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2023-04-17 BeOne Medicines Results MapKure, BeiGene and SpringWorks Present Clinical Data on BGB-3245, a Selective Next-Generation B-RAF Inhibitor, in Adult Patients with Advanced or Refractory Solid Tumors at the American Association for Cancer Research Annual Meeting 2023 beonemedicines.com ↗
We believe that our early clinical data supported the advancement into our selected expansion cohorts which are now underway.

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as BGB-3245 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06194877 ↗
1

NCT05580770 ↗

Route Oral “BGB-3245 5mg administered orally” NCT05580770 ↗