Drugs / YCT-529
last change Jul 2026 re-read 3 minutes ago

YCT-529

also known as Yct-529 free acid

Small molecule targets RARA via inhibition

Investigated by
YourChoice Therapeutics, Inc.

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT06542237 Sep 2024 → Jul 2026 overdue — YourChoice Therapeutics, Inc. Recruiting No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT06094283 Comparator Dec 2023 → Jun 2024 — YourChoice Therapeutics, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as YCT-529 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06542237 ↗
1

NCT06094283 ↗

Known as Yct-529 free acid ChEMBL registry synonym — accepted as the source's own label CHEMBL5499704 ↗
Action Inhibit “YCT-529 - a retinoic acid receptor-α antagonist” PMID 40696162 ↗ Jul 2025
Modality Small molecule “The small molecule YCT-529 stops sperm production” PMID 40696162 ↗ Jul 2025
Route Oral “single oral doses of 10, 30, 90 or 180 mg of YCT-529 in the fasted state” PMID 40696162 ↗ Jul 2025
Target RARA “YCT-529 - a retinoic acid receptor-α antagonist” PMID 40696162 ↗ Jul 2025