Drugs / Daglutril
last change Jun 2013 re-read 3 minutes ago

Daglutril

also known as Daglutrilo · SLV-306

Small molecule targets ECE1, MME via inhibition

Developed for
hypertensive disorder
Investigated by
Solvay Pharmaceuticals

Trials 2

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00160225 Jul 2005 → ? hypertensive disorder Solvay Pharmaceuticals Completed Missed primary
Phase 2 NCT00160212 Dec 2004 → ? hypertensive disorder Solvay Pharmaceuticals Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Daglutril ClinicalTrials.gov intervention name — accepted as the source's own label NCT00160212 ↗
1

NCT00160225 ↗

Known as Daglutrilo ChEMBL registry synonym — accepted as the source's own label CHEMBL3989794 ↗
Known as SLV-306 ChEMBL registry synonym — accepted as the source's own label CHEMBL3989794 ↗
Action Inhibit “We tested the effects of treatment of such patients with daglutril, a combined endothelin-converting enzyme and neutral endopeptidase inhibitor.” PMID 24622263 ↗ Jun 2013
2

“Endothelin-converting enzyme 1 inhibitor” CHEMBL3989794 ↗

“Neprilysin inhibitor” CHEMBL3989794 ↗

Modality Small molecule — CHEMBL3989794 ↗
Target ECE1 “Endothelin-converting enzyme 1 inhibitor” CHEMBL3989794 ↗
Target MME “Neprilysin inhibitor” CHEMBL3989794 ↗