Drugs / Navepegritide
last change Feb 2026 re-read 2 minutes ago

Navepegritide

Protein / enzyme biologic

Developed for
achondroplasia
Investigated by
Ascendis Pharma A/S · Ascendis Pharma Growth Disorders A/S

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) YUVIWEL 2026-02-27 fda.gov

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 25 trials
Phase 2 NCT06732895 Dec 2024 → Aug 2027 expected achondroplasia Ascendis Pharma A/S Recruiting No outcome recorded
Phase 2 NCT06433557 Jul 2024 → Nov 2025 overdue achondroplasia Ascendis Pharma Growth Disorders A/S Active not recruiting No outcome recorded
Phase 2 NCT06079398 Jan 2024 → Dec 2027 expected achondroplasia Ascendis Pharma A/S Recruiting No outcome recorded
Phase 2 NCT05246033 Jan 2022 → Mar 2023 achondroplasia Ascendis Pharma A/S Unknown No outcome recorded
Phase 2 NCT04085523 Jun 2020 → Sep 2022 achondroplasia Ascendis Pharma A/S Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT05929807 Jun 2023 → Jan 2039 expected achondroplasia Ascendis Pharma Growth Disorders A/S Enrolling by invitation No outcome recorded
Phase 2/3 NCT05598320 Mar 2023 → Aug 2024 achondroplasia Ascendis Pharma Growth Disorders A/S Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as navepegritide “Once-weekly TransCon CNP (navepegritide) in children with achondroplasia” PMID 37823031 Oct 2023
4

NCT06079398

NCT06732895

NCT05598320

NCT06433557

Known as Navepegritida ChEMBL registry synonym — accepted as the source's own label CHEMBL4594507
Known as TransCon CNP “Navepegritide (TransCon CNP) 100 micrograms per kilogram (µg/kg) delivered once weekly by subcutaneous injection” NCT05598320
4

“100 μg CNP/kg of Navepegritide (TransCon CNP) administered SC once-weekly” NCT06079398

NCT04085523

NCT05246033

NCT05929807

Known as Transcon cnp-38 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594507
Modality Protein / enzyme biologic CHEMBL4594507
Route Subcutaneous “administered by subcutaneous injection via syringe and needle.” NCT04085523