Drugs / G100
last change Jan 2023 re-read 3 minutes ago

G100

Small molecule targets TLR4 via activation

Developed for
sarcoma · follicular lymphoma
Investigated by
Immune Design · Merck Sharp & Dohme LLC · Institut Bergonié · Ministry of Health, France

Trials 3

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02387125 Feb 2015 → Mar 2019 melanoma, non-small cell lung carcinoma, ovarian cancer, sarcoma Immune Design Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02501473 Feb 2016 → Aug 2019 follicular lymphoma Immune Design Terminated No outcome recorded Stop: Business
Phase 21 trial
Phase 2 NCT02406781 Jun 2015 → Nov 2020 sarcoma Institut Bergonié Completed Mixed

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as G100 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02406781 ↗
2

NCT02387125 ↗

NCT02501473 ↗

Action Activate “toll-like receptor-4 (TLR-4) agonist” NCT02387125 ↗
Modality Small molecule “a potent synthetic small molecule” NCT02387125 ↗
Route Other “intratumoral G100” NCT02387125 ↗
Target TLR4 “toll-like receptor-4 (TLR-4) agonist” NCT02387125 ↗