Drugs / Fosravuconazole
Fosravuconazole
also known as
E1224 · Bms-379224 · E-1224 FREE ACID · Fosravuconazol · Ravuconazole methyl phosphate · Ravuconazole phosphoester
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT03892213 | Oct → Dec 2014 | Chagas disease | Drugs for Neglected Diseases | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT03086226 | May 2017 → Jun 2021 | mycetoma | Drugs for Neglected Diseases | Completed | No outcome recorded |
| Phase 2 | NCT03378661 | Nov 2016 → Jan 2018 | Chagas disease | Drugs for Neglected Diseases | Unknown | No outcome recorded |
| Phase 2 | NCT01489228 | Jun 2011 → Aug 2012 | Chagas disease | Drugs for Neglected Diseases | Unknown | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Fosravuconazole | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03086226 ↗ |
| Known as | Bms-379224 | ChEMBL registry synonym — accepted as the source's own label CHEMBL333325 ↗ |
| Known as | E-1224 FREE ACID | ChEMBL registry synonym — accepted as the source's own label CHEMBL333325 ↗ |
| Known as | E1224 | “E1224 multiple dose 400 mg loading dose once daily for 3 days (i.e. from Day 4 to Day 6 followed by maintenance dose 100mg once daily for 9 days (from Day 7 to Day15).” NCT03892213 ↗ |
| Known as | Fosravuconazol | ChEMBL registry synonym — accepted as the source's own label CHEMBL333325 ↗ |
| Known as | Ravuconazole methyl phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL333325 ↗ |
| Known as | Ravuconazole phosphoester | ChEMBL registry synonym — accepted as the source's own label CHEMBL333325 ↗ |
| Modality | Small molecule | — CHEMBL333325 ↗ |
| Route | Oral | “Patients were randomly assigned (1:1:1:1:1) to five oral treatment groups: high-dose E1224” PMID 29352704 ↗ Jan 2018 |