Drugs / [1-13C]Pyruvate
last change Dec 2024 re-read 2 minutes ago

[1-13C]Pyruvate

Diagnostic / imaging agent

Investigated by
Rigshospitalet, Denmark · Sunnybrook Health Sciences Centre

Trials 2 · a red edge is where a trial was stopped

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02648009 Apr 2016 → Apr 2027 expected hypertensive disorder Sunnybrook Health Sciences Centre Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT05396118 May 2022 → Aug 2024 breast cancer, lymphoma, neuroendocrine carcinoma, sarcoma Rigshospitalet, Denmark Unknown No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as [1-13C]pyruvate “Four healthy subjects underwent conventional proton cardiac magnetic resonance imaging followed by 13C imaging and spectroscopic acquisition immediately after intravenous...” PMID 27635086 Sep 2016
1

NCT05396118

Modality Diagnostic / imaging agent “DNP-dissolution results in an intravenous contrast agent that is "hyperpolarized", producing a magnetic signal that is enhanced by up to 100,000 fold.” NCT02648009
Route Intravenous “A 0.1 mmol/kg dose (approximately 20 mL) of this solution will be injected through an intravenous line.” NCT02648009