Drugs / DRINABANT
last change Sep 2009 re-read 3 minutes ago

DRINABANT

also known as AVE1625

Small molecule targets CNR1 via inhibition

Developed for
Alzheimer disease · hyperlipidemia · obesity disorder · schizophrenia
Investigated by
Sanofi

Trials 3

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00380302 Sep 2006 → Jul 2007 Alzheimer disease Sanofi Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00439634 Feb 2007 → Sep 2009 schizophrenia Sanofi Terminated No outcome recorded
Phase 2 NCT00345410 Jun 2006 → Jun 2007 hyperlipidemia, obesity disorder Sanofi Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as DRINABANT ChEMBL registry synonym — accepted as the source's own label CHEMBL3545166 ↗
Known as AVE1625 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00380302 ↗
2

NCT00345410 ↗

NCT00439634 ↗

Action Inhibit “AVE1625 is a new potent and selective cannabinoid 1 (CB1) antagonist in clinical development for the treatment of cognitive impairment in patients diagnosed with schizophrenia.” NCT00439634 ↗
1

“Cannabinoid CB1 receptor antagonist” CHEMBL3545166 ↗

Modality Small molecule — CHEMBL3545166 ↗
Route Oral “oral administration” NCT00439634 ↗
Target CNR1 “Cannabinoid CB1 receptor antagonist” CHEMBL3545166 ↗