Drugs / RUZOTOLIMOD
last change Jul 2024 re-read 2 minutes ago

RUZOTOLIMOD

also known as RO7020531 · RG7854

Small molecule targets TLR7

Developed for
chronic hepatitis B virus infection
Investigated by
Hoffmann-La Roche

Trials 3 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03530917 May 2018 → May 2019 Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT02956850 Dec 2016 → Jun 2021 chronic hepatitis B virus infection Hoffmann-La Roche Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04225715 Jul 2020 → Jul 2024 chronic hepatitis B virus infection Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as RUZOTOLIMOD ChEMBL registry synonym — accepted as the source's own label CHEMBL5095082
Known as RG7854 “We aimed to assess the safety and tolerability of RO7020531 (also called RG7854), a prodrug of the TLR7 agonist RO7011785” PMID 36509100 Dec 2022
Known as RO7020531 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03530917
2

NCT02956850

NCT04225715

Modality Small molecule CHEMBL5095082
Route Oral “Study medication was administered orally to participants after they had fasted.” PMID 36509100 Dec 2022
Target TLR7 “RO7020531 (also called RG7854), a prodrug of the TLR7 agonist RO7011785” PMID 36509100 Dec 2022