Drugs / Donor-derived CD34+ HSC with CRISPR/Cas9-mediated CD33 deletion
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Donor-derived CD34+ HSC with CRISPR/Cas9-mediated CD33 deletion

targets CD33 via inhibition

Developed for
acute myeloid leukemia
Investigated by
German Cancer Research Center · University Hospital Dresden · University Hospital Heidelberg

Trials 1 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05662904 Jan 2028 → Jan 2029 expected acute myeloid leukemia German Cancer Research Center Not yet recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Donor-derived CD34+ HSC with CRISPR/Cas9-mediated CD33 deletion ClinicalTrials.gov intervention name — accepted as the source's own label NCT05662904
Action Inhibit “CRISPR/Cas9-mediated inactivation of CD33 in hematopoietic stem cells (HSC)” NCT05662904
Target CD33 “CRISPR/Cas9-mediated inactivation of CD33 in hematopoietic stem cells (HSC)” NCT05662904