Drugs / TPN171H
last change Jun 2025 re-read 2 minutes ago

TPN171H

also known as TPN171
Developed for
erectile dysfunction · pulmonary arterial hypertension
Investigated by
Vigonvita Life Sciences · Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Trials 14 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT05585931 Nov → Dec 2022 erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT05750355 Oct → Dec 2022 Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT05208814 Mar → Oct 2022 erectile dysfunction, pulmonary arterial hypertension Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT05316428 Feb → Apr 2022 alcohol-related disorders, erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT05185011 Dec 2021 → Feb 2022 erectile dysfunction, pulmonary arterial hypertension Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT04655872 Nov 2020 → Jan 2021 Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT06090136 Sep → Dec 2020 erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT06090123 Jan → Apr 2020 erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded
Phase 1 NCT05948644 Apr 2019 → Oct 2020 pulmonary arterial hypertension Vigonvita Life Sciences Completed No outcome recorded
Phase 23 trials
Phase 2 NCT05388825 Aug 2022 → Jan 2023 erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded
Phase 2 NCT04483115 Nov 2020 → Jun 2022 pulmonary arterial hypertension Vigonvita Life Sciences Completed No outcome recorded
Phase 2 NCT04479917 Jul 2020 → Jul 2021 erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded
Phase 32 trials
Phase 3 NCT06301854 Apr 2024 → Jun 2025 erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded
Phase 3 NCT05188989 Dec 2021 → Feb 2023 erectile dysfunction Vigonvita Life Sciences Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 16 sources stand behind the page.

FieldValueCited text
Known as TPN171H “Single dose of 10mg TPN171H on Day 1” NCT06090123
13

NCT04483115

NCT05185011

NCT05585931

NCT06301854

NCT05208814

NCT04655872

NCT04479917

NCT05188989

NCT05388825

NCT05948644

NCT05316428

NCT06090136

NCT05750355

Known as TPN171 “This study aimed to assess the immediate impact of a single dose of TPN171 (10 mg) on semen quality in healthy male Chinese volunteers.” PMID 40181588 Apr 2025
Action Inhibit “TPN171 is a phosphodiesterase-5 inhibitor.” PMID 40277393 Apr 2025
Route Oral “Route of administration:;oralNCT04479917