Drugs / Dexpanthenol
Dexpanthenol
also known as
BAY81-2996 · BAY207543 · Bepanthen Wund- und Heilsalbe · Bepanthol · Bepantol · Bepantol Derma Spray · D-panthenol · D-pantothenyl alcohol · +5 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | BEROCCA PN | — | 1947-07-28 | fda.gov ↗ |
Trials 15 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 13 trials | ||||||
| Phase 1 | NCT06370585 | May → Jul 2024 | dry eye syndrome | Laboratorios Sophia S.A de C.V. | Completed | No outcome recorded |
| Phase 1 | NCT03520348 | Oct 2017 → May 2018 | dry eye syndrome | Laboratorios Sophia S.A de C.V. | Completed | No outcome recorded |
| Phase 1 | NCT00885937 | Apr → May 2009 | — | Bayer | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT01318889 | Sep 2010 → Sep 2011 | mucositis | Shahid Beheshti University of Medical Sciences | Unknown | No outcome recorded |
| Phase 2 | NCT00839280 | Aug → Sep 2007 | skin disorder | Bayer | Completed | No outcome recorded |
| Phase 34 trials | ||||||
| Phase 3 | NCT03439436 | Feb → May 2018 | nasal cavity disorder | McNeil AB | Completed | No outcome recorded |
| Phase 3 | NCT02601235 | Jan → Aug 2018 | nasal cavity disorder | EMS | Completed | No outcome recorded |
| Phase 3 | NCT03095872 | Mar 2017 → Jan 2018 | — | RWTH Aachen University | Completed | No outcome recorded |
| Phase 3 | NCT00661102 | Dec 2008 → Apr 2011 | breast cancer | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 44 trials | ||||||
| Phase 4 | NCT03853512 | Feb → Mar 2019 | — | Bayer | Completed | No outcome recorded |
| Phase 4 | NCT03853525 | Feb → Mar 2019 | — | Bayer | Completed | No outcome recorded |
| Phase 4 | NCT00859196 | Feb 2009 | — | Bayer | Completed | No outcome recorded |
| Phase 4 | NCT02734628 | Mar → Apr 2007 | — | Bayer | Completed | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT07395674 | Aug 2026 → Aug 2028 expected | ulcer of lower limbs | Dilara CANBAY OZDEMIR | Not yet recruiting | No outcome recorded |
| — | NCT07002632 | Jul 2021 → Jun 2024 | angular cheilitis, disorder of pharynx | Gaziosmanpasa Research and Education Hospital | Completed | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT04219358 Background | Mar 2019 → Jun 2020 | actinic cheilitis | Hospital de Clinicas de Porto Alegre | Terminated | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT00839462 Comparator | Sep 2007 | — | Bayer | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT06822608 Comparator | Feb → Nov 2025 overdue | corneal disorder | National and Kapodistrian University of Athens | Not yet recruiting | No outcome recorded |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 19 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Dexpanthenol | “The Bepanthen® Wund- und Heilsalbe (Bayer) could be a possible alternative to Vaseline® as postoperative care. Bepanthen® Wund- und Heilsalbe contains pro-vitamin Dexpanthenol...” NCT03095872 ↗15“A Study to Gain Information How Well Dexpanthenol Dermal Spray Helps the Skin to Recover After a Peeling in the External Genital Area of Women” NCT03853512 ↗ “Xylometazoline+Dexpanthenol metered nasal spray (0.1 mg+5 mg/dose) for nasal congestion.” NCT03439436 ↗ “Dexpanthenol 2% and sodium hyaluronate 0.15% ophthalmic solution.” NCT06370585 ↗ “effect of dexpanthenol dermal spray on skin recovery” NCT03853525 ↗ “Dexpanthenol” NCT02601235 ↗ |
| Known as | BAY207543 | “BAY207543 (Bepanthol, Bepantol® Derma Spray)” NCT03853512 ↗ |
| Known as | BAY81-2996 | “Dexpanthenol (Bepanthen® Wund- und Heilsalbe, BAY81-2996)” NCT02734628 ↗ |
| Known as | Bepanthen Wund- und Heilsalbe | “Dexpanthenol (Bepanthen® Wund- und Heilsalbe, BAY81-2996)” NCT02734628 ↗ |
| Known as | Bepanthol | “BAY207543 (Bepanthol, Bepantol® Derma Spray)” NCT03853512 ↗ |
| Known as | Bepantol | “dexpantenol [Bepantol]” NCT00661102 ↗ |
| Known as | Bepantol Derma Spray | “BAY207543 (Bepanthol, Bepantol® Derma Spray)” NCT03853512 ↗ |
| Known as | D-panthenol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200979 ↗ |
| Known as | D-pantothenyl alcohol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200979 ↗ |
| Known as | dexpantenol | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00661102 ↗ |
| Known as | Ilopan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200979 ↗ |
| Known as | Pantothenol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200979 ↗ |
| Known as | PRO-167 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03520348 ↗ |
| Known as | Sinecort | “Dexpanthenol (Sinecort, BAY81-2996)” NCT00885937 ↗ |
| Modality | Small molecule | — CHEMBL1200979 ↗ |
| Route | Topical | “2 applications of 2 micro liter/square centimeter on a 4X4 cm area corresponding to 32 micro liter” NCT00839280 ↗ |