Drugs / tirasemtiv
Trials 8 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 26 trials | ||||||
| Phase 2 | NCT01709149 | Oct 2012 → Mar 2014 | amyotrophic lateral sclerosis | Cytokinetics | Completed | No outcome recorded |
| Phase 2 | NCT01486849 | Nov 2011 → Mar 2012 | amyotrophic lateral sclerosis | Cytokinetics | Completed | No outcome recorded |
| Phase 2 | NCT01378676 | Jun 2011 → Mar 2012 | amyotrophic lateral sclerosis | Cytokinetics | Completed | No outcome recorded |
| Phase 2 | NCT01268280 | Dec 2010 → Oct 2012 | generalized myasthenia gravis | Cytokinetics | Terminated | No outcome recorded |
| Phase 2 | NCT01131013 | May 2010 → Mar 2011 | intermittent vascular claudication, peripheral arterial disease | Cytokinetics | Completed | No outcome recorded |
| Phase 2 | NCT01089010 | Mar → Nov 2010 | amyotrophic lateral sclerosis | Cytokinetics | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT02936635 | Oct 2016 → Oct 2018 | amyotrophic lateral sclerosis | Cytokinetics | Completed | No outcome recorded |
| Phase 3 | NCT02496767 | Sep 2015 → Mar 2017 | amyotrophic lateral sclerosis | Cytokinetics | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 10 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | tirasemtiv | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02496767 ↗ |
| Known as | CK-2017357 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01131013 ↗ |
| Action | Activate | “a novel small-molecule activator of the fast skeletal muscle troponin complex” PMID 24872402 ↗ May 2014 |
| Modality | Other / unclassified | “CK-2017357, an orally bioavailable fast skeletal muscle troponin activator” PMID 22591195 ↗ May 2012 |
| Route | Oral | “250 mg CK-2017357 in capsules administered as a single oral dose.” NCT01089010 ↗ |