Drugs / Doxylamine
Doxylamine
also known as
doxylamine succinate · Alsodorm · Decapryn · Donormil · Donormyl · Dormidina · Doxilamina · Doxy-sleep-aid · +11 more
Small molecule targets HRH1 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | DECAPRYN | — | 1948-04-07 | fda.gov ↗ |
Trials 5
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00796315 | Dec 2008 → Jun 2009 | allergic rhinitis, respiratory tract infectious disorder | Procter and Gamble | Completed | No outcome recorded |
| Phase 33 trials · 1 met primary | ||||||
| Phase 3 | NCT04401384 | Jun 2020 → Jun 2021 | hyperemesis gravidarum | Xiaoke Wu | Completed | Met primary |
| Phase 3 | NCT00857987 | Apr 2010 → Oct 2011 | respiratory tract infectious disorder | Azidus Brasil | Unknown | No outcome recorded |
| Phase 3 | NCT00614445 | Jan 2008 → Jul 2009 | hyperemesis gravidarum | Duchesnay Inc. | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT06716645 | Dec 2024 → Feb 2025 | common cold | HALEON | Completed | No outcome recorded |
| Comparator or background therapy3 trials | ||||||
| — | NCT07354529 Comparator | Jun 2025 → Jan 2026 overdue | pregnancy disorder | Bahria University | Active not recruiting | No outcome recorded |
| — | NCT06772974 Comparator | Jan → Jun 2025 overdue | hyperemesis gravidarum | Nawaz Sharif Medical College | Not yet recruiting | No outcome recorded |
| — | NCT06259747 Background | Feb → Dec 2023 | hyperemesis gravidarum | Kafrelsheikh University | Completed | No outcome recorded |
Evidence & citations 24 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | doxylamine | “Diclectin (combination of doxylamine succinate (10 mg) and pyridoxine hydrochloride (10 mg) , 2-4 tablets/day)” NCT04401384 ↗5“Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup” NCT00857987 ↗ |
| Known as | Alsodorm | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Decapryn | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Donormil | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Donormyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Dormidina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Doxilamina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Doxy-sleep-aid | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Doxylamine hydrogen succinate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | doxylamine succinate | “Diclectin (combination of doxylamine succinate (10 mg) and pyridoxine hydrochloride (10 mg) , 2-4 tablets/day)” NCT04401384 ↗3“Dextromethorphan Hydrobromide, USP 30 mg and Doxylamine Succinate, USP 12.5 mg” NCT06716645 ↗ “Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup” NCT00857987 ↗ |
| Known as | Doxylamine succinate component of bendectin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Doxylamine succinate component of bonjesta | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Doxylamine succinate component of diclectin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Doxylamine succinate component of diclegis | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Gittalun | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Hoggar n | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Meraprina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | NSC-74772 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Known as | Succinate doxilamine | “Guaifenesin - 100mg, Etafedrine hydrochloride 20mg, Succinate doxilamine 6mg.” NCT00857987 ↗ |
| Known as | Unisom | ChEMBL registry synonym — accepted as the source's own label CHEMBL1004 ↗ |
| Action | Inhibit | “Histamine H1 receptor antagonist” CHEMBL1004 ↗ |
| Modality | Small molecule | — CHEMBL1004 ↗ |
| Route | Oral | “initial oral dose of 2 tablets at bedtime” NCT04401384 ↗ |
| Target | HRH1 | “Histamine H1 receptor antagonist” CHEMBL1004 ↗ |