Drugs / Selatogrel
last change Jun 2026 re-read 2 minutes ago

Selatogrel

also known as ACT-246475

Small molecule targets P2RY12 via inhibition

Developed for
acute myocardial infarction · coronary atherosclerosis
Investigated by
Viatris Innovation GmbH · Idorsia Pharmaceuticals Ltd.

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 18 trials
Phase 1 NCT07615868 Jun → Oct 2026 expected coronary artery disorder Viatris Innovation GmbH Recruiting No outcome recorded
Phase 1 NCT07133191 Oct → Nov 2025 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT04557280 Nov → Dec 2020 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT04406896 Jul → Oct 2020 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT03814200 Jan → Feb 2019 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT03593278 Jul → Aug 2018 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT03430661 Jan 2018 → May 2019 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT01954615 Oct 2011 → Mar 2012 Idorsia Pharmaceuticals Ltd. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT03487445 Jul → Nov 2018 acute myocardial infarction Viatris Innovation GmbH Completed No outcome recorded
Phase 2 NCT03384966 Jan → Aug 2018 coronary atherosclerosis Viatris Innovation GmbH Completed No outcome recorded
Phase 31 trial
Phase 3 NCT04957719 Aug 2021 → Dec 2026 expected acute myocardial infarction Viatris Innovation GmbH Enrolling by invitation No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as Selatogrel ClinicalTrials.gov intervention name — accepted as the source's own label NCT03384966
6

NCT04557280

NCT07133191

NCT04406896

NCT04957719

NCT07615868

NCT03487445

Known as ACT-246475 “Randomized Trial to Assess the Pharmacokinetics, the Pharmacodynamics, and the Tolerability of a Single 16 mg Dose of Selatogrel (ACT-246475) in Chinese Adults With Chronic...” NCT07615868
6

“Single s.c. dose of 16 mg ACT-246475 including 3.7 MBq (100 μCi) 14C-radiolabeled ACT 246475” NCT03593278

“pharmacokinetics of selatogrel (ACT-246475).” NCT04406896

NCT03814200

NCT01954615

NCT03593278

NCT03430661

Action Inhibit “Selatogrel is a reversible P2Y12 receptor antagonist for subcutaneous administration.” NCT03384966
1

“Purinergic receptor P2Y12 antagonist” CHEMBL4297589

Modality Small molecule CHEMBL4297589
Route Oral “single, oral dose of ACT-246475” NCT01954615
Target P2RY12 “Purinergic receptor P2Y12 antagonist” CHEMBL4297589