Drugs / leteprinim
last change Jun 2005 re-read 3 minutes ago

leteprinim

Small molecule

Developed for
amnestic disorder · chemotherapy-induced neuropathy
Investigated by
National Institute on Aging (NIA) · NeoTherapeutics

Trials 2

20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00000180 ? → Jun 2005 amnestic disorder National Institute on Aging (NIA) Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00041795 Jan 2002 → ? chemotherapy-induced neuropathy NeoTherapeutics Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as leteprinim ClinicalTrials.gov intervention name — accepted as the source's own label NCT00041795 ↗
Known as AIT-082 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00000180 ↗
Known as leteprinim potassium “leteprinim potassium (Neotrofin)” NCT00041795 ↗
Known as Leteprinim potassium salt ChEMBL registry synonym — accepted as the source's own label CHEMBL2104345 ↗
Known as Neotrofin “A phase 1, randomized, double-blind, placebo-controlled, dose escalation study of the purine derivative, AIT-082 (Neotrofin, NeoTherapeutics) was conducted in mild Alzheimer's...” PMID 12770610 ↗ Jun 2003
1

“leteprinim potassium (Neotrofin)” NCT00041795 ↗

Modality Small molecule “AIT-082 is a novel small molecule that crosses the blood-brain barrier to enhance nerve function by increasing levels of neurotrophic growth factors and encouraging nerve...” NCT00000180 ↗
Route Oral “Patients received an oral dose of AIT-082 or placebo daily for one week.” PMID 12770610 ↗ Jun 2003