Drugs / VIPALANEBART
last change Aug 2025 re-read 3 minutes ago

VIPALANEBART

also known as LY3451838

Monoclonal antibody

Developed for
migraine disorder
Investigated by
Eli Lilly and Company

Trials 2

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03692949 Dec 2018 → Feb 2020 — Eli Lilly and Company Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT04498910 Nov 2020 → Nov 2022 migraine disorder Eli Lilly and Company Completed Missed primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VIPALANEBART ChEMBL registry synonym — accepted as the source's own label CHEMBL5314614 ↗
Known as LY3451838 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04498910 ↗
1

NCT03692949 ↗

Action Inhibit “LY3451838, a PACAP-neutralizing monoclonal antibody” PMID 40836866 ↗ Aug 2025
Modality Monoclonal antibody “LY3451838, a PACAP-neutralizing monoclonal antibody” PMID 40836866 ↗ Aug 2025
Route Intravenous “single increasing doses of LY3451838 will be administered intravenously (into a vein).” NCT03692949 ↗