Drugs / STX-478
last change 3 days ago re-read 2 minutes ago

STX-478

also known as LY4064809 · Tersolisib

Small molecule

Developed for
breast cancer · metastatic neoplasm
Investigated by
Eli Lilly and Company · Scorpion Therapeutics · Pfizer

Trials 8 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT07662798 Jul → Sep 2026 expected Eli Lilly and Company Recruiting No outcome recorded
Phase 1 NCT07519525 Mar → May 2026 Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT07339735 Jan → Mar 2026 Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT07247357 Oct → Dec 2025 Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06991179 May → Sep 2025 Scorpion Therapeutics Completed No outcome recorded
Phase 1 NCT06901336 Mar → May 2025 Scorpion Therapeutics Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05768139 Apr 2023 → Jul 2030 expected breast cancer Eli Lilly and Company Recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07174336 Dec 2025 → May 2029 expected breast cancer, metastatic neoplasm Eli Lilly and Company Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as STX-478 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06901336
1

NCT05768139

Known as LY4064809 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07247357
4

NCT07339735

NCT06991179

NCT07174336

NCT07519525

Known as Tersolisib ClinicalTrials.gov intervention name — accepted as the source's own label NCT07662798
Action Inhibit “STX-478 is a mutant-selective PI3Kα inhibitor” NCT05768139
Modality Small molecule CHEMBL5421037
Route Oral oral administration” NCT06901336