Drugs / Focetria

Regulatory milestones approvals, filings & regulatory actions · 3 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Withdrawn EU (EMA) Focetria 2015-08-13 europa.eu
Refused (EMA) EU (EMA) Focetria 2007-05-07 europa.eu
Approved EU (EMA) Focetria 2007-05-02 europa.eu

Trials 6 · a red edge is where a trial was stopped

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT01069601 Feb 2010 → Apr 2011 immunodeficiency disease HepNet Study House, German Liverfoundation Terminated No outcome recorded
Phase 2 NCT01006681 Nov 2009 → Apr 2010 influenza, rheumatic disorder Tel-Aviv Sourasky Medical Center Unknown No outcome recorded
Phase 32 trials
Phase 3 NCT01032408 Apr 2010 → Sep 2011 HIV infectious disease, swine influenza Chiltern Pesquisa Clinica Ltda Completed No outcome recorded
Phase 3 NCT01032395 Mar 2010 → Oct 2011 diabetes mellitus, heart disorder, lung disorder, swine influenza Chiltern Pesquisa Clinica Ltda Completed No outcome recorded
Phase 41 trial
Phase 4 NCT01022905 Nov 2009 → Feb 2010 HIV infectious disease, cancer, disease related to transplantation, rheumatic disorder University Hospital, Geneva Completed No outcome recorded
Phase not applicable1 trial
NCT01019837 Nov 2009 swine influenza Tel-Aviv Sourasky Medical Center Unknown No outcome recorded
Also used as a comparator or background therapy in 4 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT01031966 Comparator Nov 2009 → May 2010 end stage renal failure sigma-tau i.f.r. S.p.A. Completed No outcome recorded
Phase 2 NCT00914771 Comparator Sep → Dec 2009 avian influenza Novartis Vaccines Completed No outcome recorded
Phase 41 trial
Phase 4 NCT01079273 Comparator Dec 2009 → Nov 2010 influenza Opera CRO, a TIGERMED Group Company Completed No outcome recorded
Phase not applicable1 trial
NCT01012557 Comparator Nov 2009 → Sep 2010 swine influenza Copenhagen Studies on Asthma in Childhood Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as Focetria “This study aims to demonstrate the non-inferiority of two doses of H5N1 influenza antigen in non-elderly and elderly adult subjects in order to submit an extension application...” NCT00914771
8

“The purpose of this study is explore the antibody and cell mediated immune responses to one injection of Focetria™ pandemic influenza vaccine in healthy adults aged 18-60 years.” NCT01079273

“Our primary objective was to compare the immune responses conferred by MF59®-adjuvanted vaccine (Focetria®) in H1N1pnd09-naïve pregnant and non-pregnant women.” PMID 23637733 Apr 2013

“Adverse events increased with age (P=0.01) and were more frequent with Pandemrix® than Focetria® (P=0.03).” PMID 21419775 Mar 2011

NCT01069601

NCT01032408

NCT01032395

NCT01006681

NCT01012557

Known as Focetria (Monovalent MF59-Adjuvanted vaccine) ClinicalTrials.gov intervention name — accepted as the source's own label NCT01019837
Known as MF59 adjuvanted H1N1 influenza monovalent vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT01031966
Modality Vaccine “Focetria (Monovalent MF59-Adjuvanted vaccine)” NCT01006681
Route Intramuscular “Intra muscular” NCT01006681