Drugs / Kisspeptin-10
Kisspeptin-10
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT05456854 | Jun 2022 → Aug 2024 | metabolic disease | Massachusetts General Hospital | Withdrawn | No outcome recorded |
| Phase 1 | NCT04532801 | Sep 2019 → Aug 2024 | acute insulin response, glucose metabolism disease | Massachusetts General Hospital | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 33 trials | ||||||
| Phase 3 | NCT03315325 | Aug 2014 | infertility disorder | Quaid-e-Azam University | Completed | No outcome recorded |
| Phase 3 | NCT03286517 | Jun → Aug 2014 | — | Ghulam Nabi | Completed | No outcome recorded |
| Phase 3 | NCT03771326 | Oct → Nov 2013 | — | Quaid-e-Azam University | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Kisspeptin-10 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03286517 ↗ |
| Known as | Human metastin 45-54 | ChEMBL registry synonym — accepted as the source's own label CHEMBL376756 ↗ |
| Known as | Kisspeptin-10 (human) | ChEMBL registry synonym — accepted as the source's own label CHEMBL376756 ↗ |
| Known as | KP10 | “intravenous bolus administration of human kisspeptin-10 (KP10, 50 μg), and vehicle (1 ml)” PMID 21136344 ↗ Dec 2010 |
| Known as | metastin 45-54 | “Kisspeptin-10 (metastin 45-54, Calbiochem, Darmstadt, Germany) is a potent HPG-axis stimulator and control reproduction.” NCT03315325 ↗2“Kisspeptin-10 (metastin 45-54, Calbiochem, Darmstadt, Germany)” NCT03286517 ↗ “Kisspeptin-10 (metastin 45-54, Calbiochem, Darmstadt, Germany)” NCT03771326 ↗ |
| Action | Activate | “Kisspeptin-10 stimulates gonadotropin release in both male and female rodents.” PMID 21976724 ↗ Oct 2011 |
| Modality | Peptide | “Kisspeptin peptides are critical in human reproductive physiology and are potential therapies for infertility.” PMID 21976724 ↗ Oct 2011 |
| Route | Intravenous | “Kisspeptin-10 was administered (1 µg/kg BW) as an intravenous bolus” NCT03315325 ↗ |