Drugs / PERENOSTOBART
last change Aug 2023 re-read 9 days ago

PERENOSTOBART

also known as SRF617

Monoclonal antibody

Developed for
castration-resistant prostate carcinoma
Investigated by
Coherus Oncology, Inc. · Surface Oncology · Arcus Biosciences, Inc. · Merck Sharp & Dohme LLC

Trials 2

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04336098 Mar 2020 → Aug 2023 — Coherus Oncology, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05177770 Jan 2022 → Apr 2023 castration-resistant prostate carcinoma Coherus Oncology, Inc. Terminated No outcome recorded Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as PERENOSTOBART ChEMBL registry synonym — accepted as the source's own label CHEMBL5314698 ↗
Known as SRF617 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05177770 ↗
1

NCT04336098 ↗

Action Inhibit “SRF617 prevents CD39 mediated conversion of adenosine triphosphate (ATP) and adenosine diphosphate (ADP) to adenosine monophosphate (AMP) and phosphate” NCT04336098 ↗
Modality Monoclonal antibody — CHEMBL5314698 ↗