Drugs / Dryvax
last change Apr 2009 re-read 2 minutes ago

Dryvax

Vaccine

Developed for
smallpox
Investigated by
National Institute of Allergy and Infectious Diseases (NIAID) · DynPort Vaccine Company LLC, A GDIT Company

Trials 8 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT00082446 May 2004 → Aug 2007 smallpox National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT00042094 Mar 2002 → Mar 2003 smallpox DynPort Vaccine Company LLC, A GDIT Company Completed No outcome recorded
Phase 1 NCT00068198 ? → Nov 2004 smallpox National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT00000767 ? → Jul 1996 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT00437021 Apr 2007 → Apr 2009 smallpox National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 23 trials
Phase 2 NCT00032708 Apr → Nov 2004 smallpox National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00050505 Oct 2002 → Dec 2003 smallpox National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00026611 ? → Dec 2001 smallpox National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00133575 Background Oct 2005 → Apr 2008 smallpox National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00053495 Comparator Jan → Jun 2003 smallpox Emergent BioSolutions Completed No outcome recorded
Phase 2 NCT00053508 Comparator Sep 2002 → Mar 2003 smallpox Sanofi Pasteur, a Sanofi Company Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as Dryvax Dryvax®: 0.25 mL of vaccine will be administered by the standard route of scarification using a bifurcated needle on day 112 for Groups A, B, C, D and F.” NCT00082446
11

“Group B receives priming with control vaccine (DryVax), followed by boosting with an appropriate placebo.” NCT00000767

Dryvax® smallpox vaccine administered at approximately day 180, dosage 10\^8 pfu/ml.” NCT00133575

Dryvax undiluted. Cohort A receives undiluted dose of Dryvax vaccine” NCT00050505

Dryvax® Vaccinia Vaccine” NCT00437021

Dryvax®” NCT00053495

NCT00068198

NCT00053508

NCT00032708

NCT00053495

NCT00042094

NCT00026611

Known as brand name = Dryvax brand name = DryvaxNCT00053508
Known as vaccinia virus “Because of the limited amount of Dryvax vaccine (vaccinia virus) against smallpox, this study will look at the ability to dilute the vaccine making more doses available in the...” NCT00026611
Modality Vaccine “control vaccine (DryVax)” NCT00000767
Route Other “administered by the standard route of scarification” NCT00082446