Drugs / Blosozumab
last change Mar 2015 re-read 3 minutes ago

Blosozumab

also known as LY2541546

Monoclonal antibody targets SOST via inhibition

Developed for
osteoporosis
Investigated by
Eli Lilly and Company

Trials 5

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT02337387 Jan → Mar 2015 postmenopausal osteoporosis Eli Lilly and Company Terminated No outcome recorded
Phase 1 NCT02109042 Apr → Jul 2014 postmenopausal osteoporosis Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01742091 Sep 2009 → Mar 2010 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01742078 Jun 2008 → Jun 2010 — Eli Lilly and Company Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01144377 Aug 2010 → May 2012 osteoporosis Eli Lilly and Company Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Blosozumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT02109042 ↗
1

NCT02337387 ↗

Known as LY2541546 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01144377 ↗
2

NCT01742078 ↗

NCT01742091 ↗

Action Inhibit “Sclerostin inhibitor” CHEMBL1742993 ↗
Modality Monoclonal antibody — CHEMBL1742993 ↗
Route Subcutaneous “Administered subcutaneously” NCT01144377 ↗
Target SOST “Sclerostin inhibitor” CHEMBL1742993 ↗