Drugs / Amb a 1 Immunostimulatory Conjugate
last change Oct 2006 re-read 3 minutes ago

Amb a 1 Immunostimulatory Conjugate

also known as AIC

Vaccine targets TLR9 via activation

Developed for
seasonal allergic rhinitis
Investigated by
Johns Hopkins University

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00346086 May → Aug 2001 seasonal allergic rhinitis Johns Hopkins University Completed Missed primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Amb a 1 Immunostimulatory Conjugate “AIC (Amb a 1 Immunostimulatory Conjugate)” NCT00346086 ↗
Known as AIC ClinicalTrials.gov intervention name — accepted as the source's own label NCT00346086 ↗
Action Activate “Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis.” PMID 17021320 ↗ Oct 2006
Modality Vaccine “a vaccine consisting of Amb a 1, a ragweed-pollen antigen, conjugated to a phosphorothioate oligodeoxyribonucleotide immunostimulatory sequence of DNA (AIC)” PMID 17021320 ↗ Oct 2006
Route Subcutaneous “Subcutaneously Administered Dynavax Amb a 1 Immunostimulatory Oligodeoxyribonucleotide Conjugate (AIC)” NCT00346086 ↗
Target TLR9 “Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis.” PMID 17021320 ↗ Oct 2006