Drugs / Lipase
last change Apr 2026 re-read 2 minutes ago

Lipase

Protein / enzyme biologic

Developed for
acute necrotizing pancreatitis · gallstones
Investigated by
Asian Institute of Gastroenterology, India

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) COTAZYM 1996-12-09 fda.gov

Trials 2 · a red edge is where a trial was stopped

19971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT07441824 Apr 2026 → Jun 2027 expected acute necrotizing pancreatitis, exocrine pancreatic insufficiency Asian Institute of Gastroenterology, India Recruiting No outcome recorded
Phase 3 NCT07211568 Oct 2025 → Apr 2027 expected acute necrotizing pancreatitis Asian Institute of Gastroenterology, India Not yet recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
NCT03247101 Comparator Feb 2016 → Dec 2017 gallstones Min-Sheng General Hospital Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Lipase “Enteric coated enzyme preparation containing: Lipase 25000U, Amylase 18000U, Protease 1000U. These m” NCT07441824
2

“Enteric coated enzyme preparation containing: Lipase 25000U, Amylase 18000U, Protease 1000U.” NCT07211568

“Biotase 1# [Biodiastase 30mg + lipase 65mg + newlase 10mg]/tab po tid x 6 months” NCT03247101

Action Restore “pancreatic enzyme replacement therapy” NCT07211568
Modality Protein / enzyme biologic “enzyme preparation” NCT07211568
Route Oral “Biotase 1# [Biodiastase 30mg + lipase 65mg + newlase 10mg]/tab po tid x 6 months” NCT03247101