Drugs / Benfotiamine
Benfotiamine
also known as
8088 C.B · BC-DN-01 · Benfothiamine · Benfotiamina · Benphothiamine · Benzoylthiamine monophosphate · Benzoylthiamine o-monophosphate · Benzoylthiaminmonophosphat · +4 more
Trials 8
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT00117026 | Aug 2005 → Jun 2010 | type 1 diabetes mellitus | University Hospital, Aker | Completed | No outcome recorded |
| Phase 22 trials · 1 missed | ||||||
| Phase 2 | NCT06223360 | Mar 2024 → Dec 2027 expected | Alzheimer disease | Alzheimer's Disease Cooperative Study (ADCS) | Active not recruiting | No outcome recorded |
| Phase 2 | NCT02292238 | Feb 2015 → Jul 2020 | Alzheimer disease | Burke Medical Research Institute | Completed | Missed primary |
| Phase 32 trials | ||||||
| Phase 3 | NCT01868191 | Jul 2013 → Dec 2014 | diabetic polyneuropathy | Diabetes Schwerpunktpraxis | Unknown | No outcome recorded |
| Phase 3 | NCT00785460 | Jan → May 2008 | — | Ruhr University of Bochum | Completed | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT07708233 | Jul 2026 → Jun 2027 expected | diabetic polyneuropathy | Thammasat University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT00680121 | Jul 2008 → Aug 2011 | alcohol dependence | University of Kansas | Completed | No outcome recorded |
| Phase 4 | NCT00437008 | Nov 2004 → Jan 2006 | type 2 diabetes mellitus | Ruhr University of Bochum | Completed | No outcome recorded |
| Comparator or background therapy3 trials | ||||||
| Phase 1/2 | NCT01793350 Comparator | Jun 2013 → Oct 2014 | diabetic polyneuropathy | BioChemics, Inc. | Withdrawn | No outcome recorded |
| Phase 4 | NCT00565318 Comparator | Dec 2007 → Jun 2009 | diabetic kidney disease | University Medical Center Groningen | Completed | No outcome recorded |
| Phase 4 | NCT00446810 Comparator | Sep 2007 → Dec 2008 | type 2 diabetes mellitus | Ruhr University of Bochum | Unknown | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 13 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Benfotiamine | “active ingredient of BC-DN-01 : benfotiamine” NCT01793350 ↗ |
| Known as | 8088 C.B | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | BC-DN-01 | “Phase 2 - for 12 weeks - total daily dose 320mg benfotiamine as 16g BC-DN-01” NCT01793350 ↗ |
| Known as | Benfothiamine | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | Benfotiamina | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | Benphothiamine | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | Benzoylthiamine monophosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | Benzoylthiamine o-monophosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | Benzoylthiaminmonophosphat | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | Biotamin | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | NSC-758241 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | S-benzoylthiamine monophosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Known as | S-benzoylthiamine o-monophosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4303665 ↗ |
| Modality | Small molecule | “benfotiamine, a prodrug of thiamine, as a first-in-class small molecule oral treatment for early AD.” PMID 38809849 ↗ May 2024 |
| Route | Oral | “Can Oral Benfotiamine Supplementation Influence Progression of Microvascular Complications in Patients With Type 1 Diabetes?” NCT00117026 ↗ |