Drugs / ICVB-1042
last change Feb 2025 re-read 3 minutes ago

ICVB-1042

Investigated by
IconOVir Bio

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05904236 Jun 2023 → Dec 2024 — IconOVir Bio Terminated No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2022-11-10 IconOVir Bio Results IconOVir Announces New Preclinical Data Showcasing Best-in-Class Potential of ICVB-1042, its Lead Oncolytic Virus, at SITC 2022 iconovir.com ↗
2021-05-20 IconOVir Bio Results IconOVir Bio Announces Preclinical Proof-of-Concept Data for Proprietary Mutations Designed to Improve Selectivity of Novel Oncolytic Viruses, Including Lead Product Candidate ICVB-1042 iconovir.com ↗
IconOVir Bio, Inc. (IconOVir), a preclinical-stage biotechnology company pioneering the next generation of oncolytic virus (OV) therapy to improve the treatment of patients with cancer, today announced new preclinical data demonstrating proof-of-concept for a proprietary combination of two selectivity mutations, made to Adenovirus (Ad) proteins E1A and E4-ORF6/7, both of which are incorporated into its rationally designed OV product candidates.

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as ICVB-1042 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05904236 ↗
Route Intravenous “ICVB-1042 administered intravenously” NCT05904236 ↗