drugset
Drugs / Phenindione
last change Mar 2021 re-read 2 minutes ago

Phenindione

also known as Danilone · Dindevan · Fenindiona · Hedulin · NSC-41693

Small molecule targets VKORC1 via inhibition

Developed for
atrial fibrillation · atrial flutter
Investigated by
NHS Lothian · University of Edinburgh

Trials 1 · a red edge is where a trial was stopped

today NCT03153150 · Ph 3
201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT03153150 Mar 2018 → Mar 2021 atrial fibrillation, atrial flutter, intracerebral hemorrhage, subarachnoid hemorrhage University of Edinburgh Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT01758640 Comparator Feb 2010 → Jun 2012 — Yasser Elnahas Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Phenindione ClinicalTrials.gov intervention name — accepted as the source's own label NCT03153150 ↗
1

NCT01758640 ↗
Known as Danilone ChEMBL registry synonym — accepted as the source's own label CHEMBL711 ↗
Known as Dindevan ChEMBL registry synonym — accepted as the source's own label CHEMBL711 ↗
Known as Fenindiona ChEMBL registry synonym — accepted as the source's own label CHEMBL711 ↗
Known as Hedulin ChEMBL registry synonym — accepted as the source's own label CHEMBL711 ↗
Known as NSC-41693 ChEMBL registry synonym — accepted as the source's own label CHEMBL711 ↗
Action Inhibit “Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor” CHEMBL711 ↗
Modality Small molecule — CHEMBL711 ↗
Target VKORC1 “Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor” CHEMBL711 ↗