Drugs / Dual-targeting HER2 and PD-L1 CAR-T cells
last change Dec 2025 re-read 3 minutes ago

Dual-targeting HER2 and PD-L1 CAR-T cells

Cell therapy

Developed for
peritoneal carcinoma · pleural neoplasm
Investigated by
Sichuan University

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT04684459 Mar 2021 → Dec 2025 overdue peritoneal carcinoma, pleural neoplasm Sichuan University Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Dual-targeting HER2 and PD-L1 CAR-T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04684459 ↗
Action Deplete “causing rapid and durable eradication of pleural and peritoneal metastatic tumors in xenograft models” PMID 36402752 ↗ Nov 2022
Modality Cell therapy “CAR-T cells” NCT04684459 ↗
Route Intravenous “via intravenous or thoracic/peritoneal cavity infusion” NCT04684459 ↗
Route Other “via intravenous or thoracic/peritoneal cavity infusion” NCT04684459 ↗