Drugs / selepressin
last change Oct 2019 re-read 3 minutes ago

selepressin

also known as FE 202158 · Selepresina · Selepressine

Protein / enzyme biologic targets AVPR1A via activation

Developed for
infectious disease with sepsis
Investigated by
Ferring Pharmaceuticals

Trials 3

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT01612676 Jun 2012 → Nov 2013 infectious disease with sepsis Ferring Pharmaceuticals Completed No outcome recorded
Phase 2 NCT01000649 Nov 2009 → Aug 2011 infectious disease with sepsis Ferring Pharmaceuticals Completed No outcome recorded
Phase 2/31 trial · 1 missed
Phase 2/3 NCT02508649 Jul 2015 → Oct 2017 infectious disease with sepsis Ferring Pharmaceuticals Terminated Missed primary

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as selepressin ClinicalTrials.gov intervention name — accepted as the source's own label NCT02508649 ↗
Known as FE 202158 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01000649 ↗
1

NCT01612676 ↗

Known as Selepresina ChEMBL registry synonym — accepted as the source's own label CHEMBL1817709 ↗
Known as Selepressine ChEMBL registry synonym — accepted as the source's own label CHEMBL1817709 ↗
Action Activate “Selepressin, a selective vasopressin V1a receptor agonist, is a noncatecholaminergic vasopressor that may mitigate sepsis-induced vasodilatation, vascular leakage, and edema,...” PMID 31577035 ↗ Oct 2019
1

“Vasopressin V1a receptor agonist” CHEMBL1817709 ↗

Modality Protein / enzyme biologic — CHEMBL1817709 ↗
Target AVPR1A “Vasopressin V1a receptor agonist” CHEMBL1817709 ↗