Drugs / AAV1-SERCA2a
last change Jan 2026 re-read 3 minutes ago

AAV1-SERCA2a

also known as SRD-001

Gene therapy (AAV / viral vector)

Developed for
diastolic heart failure
Investigated by
Sardocor Corp.

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06061549 Aug 2023 → Aug 2025 overdue diastolic heart failure Sardocor Corp. Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AAV1-SERCA2a “A Phase 1b, Pilot Trial Evaluating the Safety and Pharmacodynamic Effects of SRD-001 (AAV1-SERCA2a) in Subjects With Heart Failure With Preserved Ejection Fraction” NCT06061549 ↗
1

NCT06061549 ↗

Known as SRD-001 “A Phase 1b, Pilot Trial Evaluating the Safety and Pharmacodynamic Effects of SRD-001 (AAV1-SERCA2a) in Subjects With Heart Failure With Preserved Ejection Fraction” NCT06061549 ↗
Modality Gene therapy (AAV / viral vector) “AAV1.SERCA2a, an Adeno-Associated Virus Serotype 1 (AAV1) vector” PMID 41546750 ↗ Jan 2026
Route Other “Patients receive a one-time intracoronary infusion of AAV1.SERCA2A.” PMID 41546750 ↗ Jan 2026