CIK cells
Trials 47 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT03282435 Comparator | Jan 2018 → Jan 2023 | non-small cell lung carcinoma | Dalian University | Unknown | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT03524274 Comparator | Apr 2018 → May 2020 | colorectal cancer | Fuda Cancer Hospital, Guangzhou | Withdrawn | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 51 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | CIK cells | “Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD8+ T cells with diverse TCR specificities, possessing non-MHC-restricted cytolytic activities...” PMID 24720900 ↗ Apr 201419“Patients receive autologous dendritic cells (DC) loaded with autologous tumor lysate (DC vaccine) by endermic injection and infusion of CIK cells.” NCT02487550 ↗ “ex vivo expanded autologous Cytokine-induced killer (CIK) cells as an adoptive cellular immunotherapy” NCT00815321 ↗ “CIK cells: intravenous infusions; D14-16; one cycle every month,at least 6 cycles;” NCT01871480 ↗ “CIK cells was activated by PD-1 inhibitor and bispecific antibody of anti-CD3/MUC1” NCT03524274 ↗ “infusion of CIK cells” NCT00862303 ↗ |
| Known as | Autologous cytokine-induced killer cell | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01592422 ↗ |
| Known as | CIK | “Combinations of Dendritic and Cytokine-induced Killer Cells (DC-CIK) and Cytokine-induced Killer Cells (CIK) treatment may enhance the immune response and stop cancer cells...” NCT03047525 ↗10“CIK cells transfected with cytokine genes possess an improved proliferation rate and a higher cytotoxic activity as compared to regular CIK cells.” NCT02487992 ↗ “Immunotherapy with cytokine-induced killer cells (CIK) may improve tumor control and survival, as well as a better quality of life.” NCT01871480 ↗ “Cytokine induced killer cells ( CIK) characterized as fast amplification, strong anti-cancer activity and broad anti-tumor spectrum” NCT01533727 ↗ “Cytokine-induced killer (CIK) cells exhibit high proliferation rate and cytotoxic activity in vitro.” NCT01868490 ↗ “cytokine-induced killer (CIK) cells are an effective tool against various types of solid tumors” PMID 26842696 ↗ Feb 2016 “Treatment of Colorectal Cancer With Autologous Cytokine Induced Killer Cells (CIK)” NCT05676190 ↗ “chemotherapy plus 3 cycles of Cytokine-induced Killer Cells(CIK) treatment” NCT02489890 ↗ “cytokine-induced killer cell (CIK) treatment” NCT00769106 ↗ “cytokine-induced killer cells (CIK) therapy” NCT01929499 ↗ “Cytokine-Induced Killer Cell (CIK)” NCT02487550 ↗ |
| Known as | Cytokine-induced killer | “Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD8+ T cells with diverse TCR specificities, possessing non-MHC-restricted cytolytic activities...” PMID 24720900 ↗ Apr 2014 |
| Known as | cytokine-induced killer (CIK) cells | “Thus, we aimed to find an innovative strategy to refine therapeutic applications and improve their outcomes by examining the potential of cytokine-induced killer (CIK) cells.” PMID 41520915 ↗ Jan 20261“ex vivo expanded autologous Cytokine-induced killer (CIK) cells as an adoptive cellular immunotherapy” NCT00815321 ↗ |
| Known as | Cytokine-Induced Killer Cell | “Cytokine-Induced Killer Cell (CIK)” NCT02487550 ↗ |
| Known as | cytokine-induced killer cells | “CIK cells (cytokine induced killer cells, CIK) are a population of heterogeneous cells generated by the in vitro amplification of mononuclear cells in peripheral blood.” NCT01655628 ↗25“Immunotherapy with cytokine-induced killer cells (CIK) may improve tumor control and survival, as well as a better quality of life.” NCT01871480 ↗ “Cytokine induced killer cells ( CIK) characterized as fast amplification, strong anti-cancer activity and broad anti-tumor spectrum” NCT01533727 ↗ “cultured cytokine-induced killer cells for 15-20 days. Cells were infused back to the patients” NCT03757858 ↗ “Treatment of Colorectal Cancer With Autologous Cytokine Induced Killer Cells (CIK)” NCT05676190 ↗ “Treatment of Colorectal Cancer With Autologous Cytokine Induced Killer Cells (CIK)” NCT05676190 ↗ “cytokine-induced killer cells (CIK) therapy” NCT01929499 ↗ |
| Action | Deplete | “Cytokine-induced killer ( CIK ) cells have been shown by our lab to be cytolytic against both autologous and allogeneic acute myeloid leukemia ( AML ) cells.” NCT00460694 ↗ |
| Modality | Cell therapy | “use of activated T-cells to treat relapsed malignancy (cancer)” NCT00185757 ↗ |
| Route | Other | “then infused into patients” NCT00460694 ↗ |