Drugs / Trimipramine
Trimipramine
also known as
7162 RP · IL 6001 · NSC-758386 · Stangyl · Surmontil · Trimeproprimine · Trimipramina · TRIMIPRAMINE MALEATE
Small molecule targets DRD2, HRH1, HTR2A, HTR2C, SLC6A2 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | SURMONTIL | — | 1979-06-12 | fda.gov ↗ |
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT07263438 | Nov 2025 → Mar 2028 expected | glioblastoma | Centre Hospitalier Universitaire Vaudois | Recruiting | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT02237937 | Sep 2011 → Dec 2014 | major depressive disorder | HolsboerMaschmeyer NeuroChemie GmbH | Unknown | No outcome recorded |
Evidence & citations 17 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Trimipramine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07263438 ↗ |
| Known as | 7162 RP | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Known as | IL 6001 | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Known as | NSC-758386 | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Known as | Stangyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Known as | Surmontil | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Known as | Trimeproprimine | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Known as | Trimipramina | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Known as | TRIMIPRAMINE MALEATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL644 ↗ |
| Action | Inhibit | “Serotonin 2c (5-HT2c) receptor antagonist” CHEMBL644 ↗4“Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL644 ↗ “Norepinephrine transporter inhibitor” CHEMBL644 ↗ “Histamine H1 receptor antagonist” CHEMBL644 ↗ “Dopamine D2 receptor antagonist” CHEMBL644 ↗ |
| Modality | Small molecule | — CHEMBL644 ↗ |
| Route | Oral | “daily oral intake” NCT07263438 ↗ |
| Target | DRD2 | “Dopamine D2 receptor antagonist” CHEMBL644 ↗ |
| Target | HRH1 | “Histamine H1 receptor antagonist” CHEMBL644 ↗ |
| Target | HTR2A | “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL644 ↗ |
| Target | HTR2C | “Serotonin 2c (5-HT2c) receptor antagonist” CHEMBL644 ↗ |
| Target | SLC6A2 | “Norepinephrine transporter inhibitor” CHEMBL644 ↗ |