Drugs / INO-4500
last change Oct 2025 re-read 3 minutes ago

INO-4500

Vaccine

Developed for
Lassa fever
Investigated by
Coalition for Epidemic Preparedness Innovations · Inovio Pharmaceuticals

Trials 2

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04093076 Jan 2021 → Oct 2022 Lassa fever Inovio Pharmaceuticals Completed No outcome recorded
Phase 1 NCT03805984 May 2019 → Oct 2020 Lassa fever Inovio Pharmaceuticals Completed No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2022-11-17 Inovio Pharmaceuticals Results INOVIO Provides an Update on Lassa Fever and MERS Programs inovio.com ↗
Although INO-4500 and INO-4700 were well-tolerated by participants in our clinical trials and generated immune responses, the two-dose regimen did not meet CEPI's selection criteria for further development.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as INO-4500 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03805984 ↗
1

NCT04093076 ↗

Modality Vaccine “synthetic DNA-based vaccine” PMID 41208990 ↗ Oct 2025
Route Other “intradermal (ID) injection” NCT03805984 ↗