Drugs / TP-1287
last change Jan 2024 re-read 3 minutes ago

TP-1287

Small molecule targets CDK9 via inhibition

Developed for
dedifferentiated liposarcoma · Ewing sarcoma · synovial sarcoma
Investigated by
Sumitomo Pharma America, Inc.

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03604783 Dec 2018 → Jan 2024 Ewing sarcoma, dedifferentiated liposarcoma, synovial sarcoma Sumitomo Pharma America, Inc. Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as TP-1287 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03604783 ↗
Known as Alvocidib phosphate ChEMBL registry synonym — accepted as the source's own label CHEMBL4594423 ↗
Known as Alvocidib prodrug tp-1287 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594423 ↗
Action Inhibit “the CDK9 inhibitor” NCT03604783 ↗
Modality Small molecule — CHEMBL4594423 ↗
Route Oral “TP-1287 by oral administration” NCT03604783 ↗
Target CDK9 “the CDK9 inhibitor” NCT03604783 ↗