Drugs / Aroxybutynin
last change Jul 2026 re-read 2 minutes ago

Aroxybutynin

Small molecule

Developed for
obstructive sleep apnea syndrome
Investigated by
Apnimed

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT04631107 Dec 2020 → May 2021 obstructive sleep apnea syndrome Apnimed Completed No outcome recorded
Phase 32 trials
Phase 3 NCT06566820 Jul 2024 → Jun 2026 overdue obstructive sleep apnea syndrome Apnimed Enrolling by invitation No outcome recorded
Phase 3 NCT05813275 Sep 2023 → Mar 2025 obstructive sleep apnea syndrome Apnimed Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04580394 Comparator Oct 2020 → May 2021 obstructive sleep apnea syndrome Apnimed Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Aroxybutynin “The current study is with aroxybutynin (AD109), a new enantiomerically pure form of oxybutynin with better safety profile compared to racemic oxybutynin.” PMID 35975547 Dec 2022
2

Aroxybutynin and atomoxetine (AD109) for obstructive sleep apnea: a randomized” PMID 42148495 Jul 2026

NCT06566820

Known as Aroxybutynin component of ad-109 ChEMBL registry synonym — accepted as the source's own label CHEMBL185434
Known as Aroxybutynina ChEMBL registry synonym — accepted as the source's own label CHEMBL185434
Known as Aroxybutynine ChEMBL registry synonym — accepted as the source's own label CHEMBL185434
Known as R-oxybutynin ClinicalTrials.gov intervention name — accepted as the source's own label NCT04580394
Modality Small molecule CHEMBL185434
Route Oral Oral administration before bed” NCT04580394