Drugs / rezivertinib
last change Dec 2025 re-read 2 minutes ago

rezivertinib

also known as BPI-7711

Small molecule targets EGFR via inhibition

Developed for
non-small cell lung carcinoma
Investigated by
Beta Pharma Shanghai · Beta Pharma, Inc. · The First Affiliated Hospital of Guangzhou Medical University

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04135820 Dec 2019 → Mar 2020 non-small cell lung carcinoma Beta Pharma, Inc. Completed No outcome recorded
Phase 1 NCT04135833 Dec 2019 → Jul 2020 non-small cell lung carcinoma Beta Pharma, Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03386955 Aug 2017 → Dec 2021 non-small cell lung carcinoma Beta Pharma Shanghai Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03812809 Jul 2019 → Jan 2022 non-small cell lung carcinoma Beta Pharma Shanghai Completed No outcome recorded
Phase 32 trials
Phase 3 NCT06955325 May 2025 → Dec 2030 expected non-small cell lung carcinoma The First Affiliated Hospital of Guangzhou Medical University Not yet recruiting No outcome recorded
Phase 3 NCT03866499 Apr 2021 → Nov 2023 overdue non-small cell lung carcinoma Beta Pharma Shanghai Active not recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as rezivertinib “This study aimed to compare the efficacy and safety of rezivertinib (BPI-7711) and gefitinib as first-line therapies in patients with EGFR-mutated locally advanced or...” PMID 39914443 Feb 2025
2

Rezivertinib (BPI-7711) is a novel third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI).” PMID 37163774 Apr 2023

NCT06955325

Known as BPI-7711 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03812809
4

NCT03386955

NCT04135833

NCT03866499

NCT04135820

Action Inhibit “tyrosine kinase inhibitor (TKI)” PMID 37163774 Apr 2023
Modality Small molecule “tyrosine kinase inhibitor (TKI)” PMID 37163774 Apr 2023
Route Oral “BPI-7711 (180 mg, orally, once daily)” NCT03812809
Target EGFR “epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor” PMID 37163774 Apr 2023