Drugs / [F-18]PBR06
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT03876002 | Jun 2016 → Feb 2018 | amyotrophic lateral sclerosis | Molecular NeuroImaging | Completed | No outcome recorded |
| Phase 1 | NCT01028209 | Nov 2009 → Sep 2010 | Alzheimer disease, Parkinson disease, multiple sclerosis | Institute for Neurodegenerative Disorders | Terminated | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT04144257 | Mar 2020 → Apr 2021 | multiple sclerosis | Brigham and Women's Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT02649985 | May 2016 → Dec 2027 expected | Alzheimer disease, multiple sclerosis | Brigham and Women's Hospital | Recruiting | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT02513589 | Sep 2017 → Jul 2018 | ischemic stroke | University Hospital, Bordeaux | Terminated | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT04616456 Background | Dec 2020 → Jan 2022 | multiple system atrophy, cerebellar type, multiple system atrophy, parkinsonian type | Brigham and Women's Hospital | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT03983252 Background | Dec 2021 → May 2024 | multiple sclerosis | Brigham and Women's Hospital | Withdrawn | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | [F-18]PBR06 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04616456 ↗ |
| Known as | [18F]-PBR06 | “This study sought to assess the usefulness of the 18 kDa translocator protein (TSPO) tracers [11C]-PBR28 and [18F]-PBR06 for imaging inflammatory vascular disease in vitro and in vivo” PMID 33950298 ↗ May 2021 |
| Known as | Peripheral benzodiazepine receptor-06 | “To measure the dynamic uptake and washout of \[18F]PBR06 (Peripheral benzodiazepine receptor-06) in brain using positron emission tomography (PET) in patients with ALS and...” NCT03876002 ↗ |
| Modality | Diagnostic / imaging agent | “Two patients with carotid stenosis associated with ischemic stroke were imaged with [18F]-PBR06 PET/CT” PMID 33950298 ↗ May 2021 |
| Route | Intravenous | “injected intravenously as a bolus” NCT03876002 ↗ |
| Target | TSPO | “the 18 kDa translocator protein (TSPO) tracers [11C]-PBR28 and [18F]-PBR06 for imaging inflammatory vascular disease in vitro and in vivo” PMID 33950298 ↗ May 2021 |