Drugs / Gumarontinib

Trials 12

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT05507294 Mar → May 2021 — Haihe Biopharma Co., Ltd. Completed No outcome recorded
Phase 1 NCT03457532 Dec 2017 → Sep 2023 neoplasm Haihe Biopharma Co., Ltd. Completed No outcome recorded
Phase 1 NCT03466268 Sep 2017 → Jan 2023 neoplasm Haihe Biopharma Co., Ltd. Completed No outcome recorded
Phase 1/24 trials
Phase 1/2 NCT06980532 Apr 2025 → Dec 2028 expected colorectal cancer Liu Huang Recruiting No outcome recorded
Phase 1/2 NCT04797702 Apr 2021 → Jul 2023 non-small cell lung carcinoma Shanghai Junshi Bioscience Co., Ltd. Unknown No outcome recorded
Phase 1/2 NCT04338243 Nov 2019 → Dec 2020 — Haihe Biopharma Co., Ltd. Unknown No outcome recorded
Phase 1/2 NCT04270591 Jul 2019 → Oct 2023 overdue — Haihe Biopharma Co., Ltd. Recruiting No outcome recorded
Phase 23 trials
Phase 2 NCT06947291 Jun 2025 → Apr 2027 expected cancer CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT06525350 Jul 2024 → Dec 2026 expected non-small cell lung carcinoma CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT06452433 Jun 2024 → Dec 2027 expected non-small cell lung carcinoma Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not yet recruiting No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT06908772 Apr 2025 → Dec 2028 expected — Shanghai JMT-Bio Inc. Not yet recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT06829459 Apr 2025 → Feb 2028 expected non-small cell lung carcinoma Shanghai JMT-Bio Inc. Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2021-03-02 Haihe Biopharma Co., Ltd. Results 新春双响炮 haihepharma.com ↗
在17例疗效可评估的患者中,有2例患者肿瘤病灶明显缩小达到部分缓解(PR):其中一例持续接受SCC244 300mg剂量达7.3个月;另一例为一代、三代EGFR-TKI多线治疗后进展的患者,持续接受SCC244 200mg 达11.1个月。

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 14 sources stand behind the page.

FieldValueCited text
Known as Gumarontinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT03466268 ↗
2

NCT03457532 ↗

NCT06452433 ↗

Known as Glumetinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT05507294 ↗
8

NCT06980532 ↗

NCT04338243 ↗

NCT06908772 ↗

NCT06525350 ↗

NCT06829459 ↗

NCT06947291 ↗

NCT04797702 ↗

NCT04270591 ↗

Known as Sc-c244 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594400 ↗
Action Inhibit “MET inhibitor” PMID 39091606 ↗ Jul 2024
Modality Small molecule — CHEMBL4594400 ↗
Route Oral “a highly selective oral MET inhibitor” PMID 39091606 ↗ Jul 2024
Target MET “MET inhibitor” PMID 39091606 ↗ Jul 2024