Drugs / VS-5584
last change Dec 2016 re-read 2 minutes ago

VS-5584

Small molecule targets MTOR via inhibition

Developed for
lymphoma · malignant mesothelioma · metastatic malignant neoplasm
Investigated by
Verastem, Inc.

Trials 2 · a red edge is where a trial was stopped

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02372227 Jan → Oct 2015 malignant mesothelioma Verastem, Inc. Terminated No outcome recorded
Phase 1 NCT01991938 Nov 2013 → Dec 2016 lymphoma, metastatic malignant neoplasm Verastem, Inc. Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as VS-5584 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02372227
1

NCT01991938

Action Inhibit “Serine/threonine-protein kinase mTOR inhibitor” CHEMBL3393066
1

“VS-5584, a PI3K/mTOR kinase inhibitor” NCT01991938

Modality Small molecule CHEMBL3393066
Route Oral Oral VS-5584 administered once daily on Day 1, 3, 5, 8, 10, 12, 15, 17 and 19 of each cycle” NCT01991938
Target MTOR “Serine/threonine-protein kinase mTOR inhibitor” CHEMBL3393066