Drugs / RP7214
last change Nov 2025 re-read 3 minutes ago

RP7214

targets DHODH via inhibition

Developed for
acute myeloid leukemia · chronic myelomonocytic leukemia · COVID-19 · myelodysplastic syndrome
Investigated by
Rhizen Pharmaceuticals SA · Incozen Therapeutics Pvt Ltd

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04680429 Dec 2020 → Jul 2021 — Rhizen Pharmaceuticals SA Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05246384 Jan 2023 → Dec 2024 acute myeloid leukemia, chronic myelomonocytic leukemia, myelodysplastic syndrome Rhizen Pharmaceuticals SA Withdrawn No outcome recorded
Phase 21 trial
Phase 2 NCT05007236 Sep 2021 → Mar 2022 COVID-19 Rhizen Pharmaceuticals SA Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as RP7214 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05246384 ↗
2

NCT04680429 ↗

NCT05007236 ↗

Action Inhibit “RP7214 is a potent and selective inhibitor of human DHODH” PMID 36217901 ↗ Nov 2022
Route Oral “single and multiple ascending oral doses of RP7214” NCT04680429 ↗
Target DHODH “RP7214 is a potent and selective inhibitor of human DHODH” PMID 36217901 ↗ Nov 2022