Drugs / Mesothelin and Claudin 18.2 CAR-T cells
last change Apr 2025 re-read 3 minutes ago

Mesothelin and Claudin 18.2 CAR-T cells

Cell therapy targets MSLN

Developed for
pancreatic ductal adenocarcinoma
Investigated by
Essen Biotech

Trials 1

202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT07066995 Apr 2025 → Dec 2027 expected pancreatic ductal adenocarcinoma Essen Biotech Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Mesothelin and Claudin 18.2 CAR-T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT07066995 ↗
Modality Cell therapy “Chimeric Antigen Receptor T (CAR T) cells” NCT07066995 ↗
Route Intravenous “Mesothelin and Claudin 18.2 CAR T cells intravenously (IV) over a duration of 10-20 minutes on day 0” NCT07066995 ↗
Target MSLN “Mesothelin (MSLN) and Claudin 18.2 (CLDN18.2) are tumor-associated antigens overexpressed in pancreatic adenocarcinoma cells.” NCT07066995 ↗