Drugs / AS-703988
last change Jul 2013 re-read 3 minutes ago

AS-703988

also known as MSC2015103B

targets MAP2K1, MAP2K2 via inhibition

Developed for
neoplasm
Investigated by
EMD Serono

Trials 1

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01453387 Sep 2011 → Jul 2013 neoplasm EMD Serono Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AS-703988 ChEMBL registry synonym — accepted as the source's own label CHEMBL3545243 ↗
Known as MSC2015103B ClinicalTrials.gov intervention name — accepted as the source's own label NCT01453387 ↗
Action Inhibit “Dual specificity mitogen-activated protein kinase kinase 2 inhibitor” CHEMBL3545243 ↗
2

“Dual specificity mitogen-activated protein kinase kinase 1 inhibitor” CHEMBL3545243 ↗

“Oral MEK Inhibitor MSC2015103B” NCT01453387 ↗

Route Oral “MSC2015103B will be administered orally once weekly” NCT01453387 ↗
Target MAP2K1 “Dual specificity mitogen-activated protein kinase kinase 1 inhibitor” CHEMBL3545243 ↗
Target MAP2K2 “Dual specificity mitogen-activated protein kinase kinase 2 inhibitor” CHEMBL3545243 ↗