Drugs / DS-1205c
last change Mar 2023 re-read 2 minutes ago

DS-1205c

Small molecule targets AXL via inhibition

Developed for
non-small cell lung carcinoma
Investigated by
Daiichi Sankyo

Trials 2 · a red edge is where a trial was stopped

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03255083 Apr 2019 → Sep 2020 non-small cell lung carcinoma Daiichi Sankyo Terminated No outcome recorded
Phase 1 NCT03599518 Sep 2018 → Apr 2020 non-small cell lung carcinoma Daiichi Sankyo Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as DS-1205c ClinicalTrials.gov intervention name — accepted as the source's own label NCT03599518
1

NCT03255083

Action Inhibit “an oral AXL-receptor inhibitor” PMID 36892745 Mar 2023
Modality Small molecule “DS-1205c is a novel, specific, orally bioavailable, small-molecule AXL receptor TKI.” PMID 36621830 Jan 2023
Route Oral “Participants receive DS-1205c (at planned doses given orally twice daily: 200 mg, 400 mg, 800 mg, 1200 mg)” NCT03255083
Target AXL “an AXL kinase inhibitor” PMID 36892745 Mar 2023