Mineral Trioxide Aggregate
Trials 19
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT05878158 | Apr 2023 → Jan 2024 | exposure, dental pulp | Ahmad Elheeny | Unknown | No outcome recorded |
| Phase 11 trial | ||||||
| Phase 1 | NCT06029023 | Dec 2022 → Sep 2024 | exposure, dental pulp | Al-Azhar University | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT05830695 | Jan → Jul 2022 | tooth disorder | nora mostafa mohammed abo shanady | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT04308863 | Nov 2018 → Oct 2020 | pulpitis | Nourhan M.Aly | Completed | No outcome recorded |
| Phase 2 | NCT02887456 | Sep 2016 → Jun 2017 | dental pulp disorder | University of Sao Paulo | Completed | No outcome recorded |
| Phase 2 | NCT01730287 | May 2010 → Dec 2012 | dental pulp necrosis | Azad University of Medical Sciences | Unknown | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT02492841 | Apr 2014 → Apr 2016 | dental caries, exposure, dental pulp | Universidad de los Andes, Chile | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00472173 | May 2007 → Nov 2010 | dental pulp necrosis | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 45 trials | ||||||
| Phase 4 | NCT04863222 | Nov 2021 → Aug 2026 overdue | dental pulp calcification | Geisinger Clinic | Recruiting | No outcome recorded |
| Phase 4 | NCT05222243 | Jan 2019 → Aug 2020 | dental pulp disorder | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT02298504 | Jul 2018 → Dec 2026 expected | dental pulp calcification | University of Maryland, Baltimore | Active not recruiting | No outcome recorded |
| Phase 4 | NCT02286648 | Feb 2014 → Jul 2015 | pulpitis | Mashhad University of Medical Sciences | Unknown | No outcome recorded |
| Phase 4 | NCT03426046 | Nov 2013 → Apr 2016 | dental caries | Didem Sakaryali | Completed | No outcome recorded |
| Phase not applicable6 trials | ||||||
| — | NCT07853183 | Oct 2026 → Apr 2027 expected | periapical periodontitis | Foundation University Islamabad | Not yet recruiting | No outcome recorded |
| — | NCT06372561 | May 2023 → Sep 2024 overdue | dental caries, dental pulp disorder | Suez Canal University | Recruiting | No outcome recorded |
| — | NCT07120321 | Jan 2022 → Jan 2025 | dental caries, pulpitis | Sacide Duman | Completed | No outcome recorded |
| — | NCT05006755 | Sep 2021 | — | Amany hasanean Abd El sadek | Unknown | No outcome recorded |
| — | NCT03403985 | Jun 2017 | dental caries, dental pulp disorder | Jordan University of Science and Technology | Unknown | No outcome recorded |
| — | NCT03606681 | Jul 2013 → Jun 2014 | dental pulp disorder | Altinbas University | Completed | No outcome recorded |
| Comparator or background therapy12 trials | ||||||
| Phase 1 | NCT07557290 Comparator | Apr → Jun 2026 overdue | exposure, dental pulp | Dr Nida Farooq | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT06116695 Comparator | Jan 2022 → Jun 2023 | dental pulp disorder | Tanta University | Completed | No outcome recorded |
| Phase 2 | NCT07541976 Comparator | Mar 2024 → Sep 2026 | dental pulp calcification | Al-Mustansiriyah University | Completed | No outcome recorded |
| Phase 2 | NCT03580135 Comparator | Nov 2018 → Jan 2019 | dental pulp disorder | Cairo University | Unknown | No outcome recorded |
| Phase 2/3 | NCT04903808 Comparator | Sep 2021 → Oct 2022 | dental caries | Cairo University | Unknown | No outcome recorded |
| Phase 2/3 | NCT03838068 Comparator | Jan 2017 → Dec 2018 | exposure, dental pulp | Gihan M Abuelniel ,PhD | Completed | No outcome recorded |
| Phase 4 | NCT06435065 Comparator | Apr 2024 → Apr 2025 | pulpitis | DR SURINDER SACHDEVA | Completed | No outcome recorded |
| Phase 4 | NCT04773886 Comparator | Feb 2020 → Mar 2021 | pulpitis | Maharishi Markendeswar University (Deemed to be University) | Completed | No outcome recorded |
| — | NCT05425368 Comparator | Aug 2022 → Oct 2023 | dental caries | Cairo University | Unknown | No outcome recorded |
| — | NCT03488316 Comparator | May → Jul 2018 | — | PAULO VINICIUS SOARES | Unknown | No outcome recorded |
| — | NCT03589560 Comparator | Jan 2015 → Aug 2017 | dental pulp necrosis | Cairo University | Completed | No outcome recorded |
| — | NCT00812877 Comparator | May 2009 → May 2012 | exposure, dental pulp | Oregon Health and Science University | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 33 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | mineral trioxide aggregate | “The aim of this study is to evaluate the clinical and radiographic outcomes of Chitosan scaffold and Mineral trioxide aggregate (MTA) when used as pulpotomy agents in mature...” NCT04308863 ↗31“Therefore, this study aimed to assess the clinical and tomographic outcomes of apexogenesis with human treated dentin matrix (hTDM) compared to mineral trioxide aggregate (MTA).” PMID 40335983 ↗ May 2025 “Endodontic Treatment of Primary Teeth Using Mineral Trioxide Aggregate Paste - Protocol of a Phase 2 Randomized Clinical Trial” NCT02887456 ↗ “Manipulation of the temporary material based on Mineral trioxide aggregate according to the manufacturer's recommendations.” NCT03488316 ↗ “Mineral trioxide aggregate (MTA) was introduced to the dental practice in the 1990s as a root-end filling material.” NCT05222243 ↗ “Mineral Trioxide Aggregate (MTA) is a calcium-silicate cement recognized for its biocompatibility and bioactivity.” NCT07541976 ↗ “Evaluation of Pulpotomy Techniques (Formocresol, Ferric Sulphate, Mineral Trioxide Aggregate)” NCT07853183 ↗ “Partial pulpotomy treatment with Mineral Trioxide Aggregate” NCT03426046 ↗ “Mineral trioxide aggregate (MTA)” NCT06029023 ↗ “Mineral Trioxide Aggregate” NCT05878158 ↗ |
| Known as | (ProRoot MTA) | “Mineral Trioxide Aggregate (ProRoot MTA)” NCT03606681 ↗ |
| Known as | MTA | “The aim of this randomized controlled trial is to compare partial pulpotomy treatments with Biodentine®, calcium hydroxide (CH) and Mineral Trioxide Aggregate (MTA) in...” NCT03426046 ↗8“The aim of this study is to evaluate the clinical and radiographic outcomes of Chitosan scaffold and Mineral trioxide aggregate (MTA) when used as pulpotomy agents in mature...” NCT04308863 ↗ “The aim of this prospective randomized clinical trial is to compare Mineral Trioxide Aggregate(MTA)with Calcium Hydroxide(CH)as materials used to induce root-end closure in...” PMID 21752247 ↗ Jul 2011 “Therefore, this study aimed to assess the clinical and tomographic outcomes of apexogenesis with human treated dentin matrix (hTDM) compared to mineral trioxide aggregate (MTA).” PMID 40335983 ↗ May 2025 “Mineral trioxide aggregate (MTA) was introduced to the dental practice in the 1990s as a root-end filling material.” NCT05222243 ↗ “Mineral Trioxide Aggregate (MTA) is a calcium-silicate cement recognized for its biocompatibility and bioactivity.” NCT07541976 ↗ “Intervention 2 : Mineral Trioxide Aggregate (MTA)” NCT07557290 ↗ “mineral trioxide aggregate (MTA)” NCT04863222 ↗ “MTA” NCT03838068 ↗ |
| Action | Activate | “Mineral Trioxide Aggregate stimulates cementoblasts to produce matrix for cementum formation and is biocompatible with the periradicular tissues thus shows a superior sealing...” NCT05006755 ↗ |
| Modality | Other / unclassified | “Mineral trioxide aggregate Root canal repair material” NCT02492841 ↗ |
| Route | Other | “that applied on dental pulp for tissue regeneration” NCT06372561 ↗ |