Drugs / EGFRt/19-28z/IL-12 CAR T-lymphocytes
last change Jan 2025 re-read 3 minutes ago

EGFRt/19-28z/IL-12 CAR T-lymphocytes

Cell therapy targets CD19

Developed for
chronic lymphocytic leukemia/small lymphocytic lymphoma · follicular lymphoma · high grade B-cell lymphoma · mantle cell lymphoma · Richter transformation
Investigated by
Roswell Park Cancer Institute

Trials 1

20252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06343376 Nov 2024 → Jan 2025 Richter transformation, chronic lymphocytic leukemia/small lymphocytic lymphoma, follicular lymphoma, high grade B-cell lymphoma +1 Roswell Park Cancer Institute Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as EGFRt/19-28z/IL-12 CAR T-lymphocytes ClinicalTrials.gov intervention name — accepted as the source's own label NCT06343376 ↗
Modality Cell therapy “Chimeric Antigen Receptor (CAR) T-cell Therapy is a type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory so they will...” NCT06343376 ↗
Route Intravenous “intravenously (IV)” NCT06343376 ↗
Target CD19 “CD19-targeted” NCT06343376 ↗